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Drug-induced autoimmune hemolytic anemia also known as Drug-induced immune hemolytic anemia (DIIHA) is a rare cause of hemolytic anemia.It is difficult to differentiate from other forms of anemia which can lead to delays in diagnosis and treatment.
Drug-induced nonautoimmune hemolytic anemia is a uncommon cause of hemolytic anemia. In drug-induced nonautoimmune hemolytic anemia, red blood cells (RBC) are destroyed from various non-immune mechanisms such as direct oxidative stress from certain drugs. [1] This is in contrast to drug-induced autoimmune hemolytic anemia where certain drugs ...
The most common antibody isotype involved in warm antibody AIHA is IgG, though sometimes IgA is found. The IgG antibodies attach to a red blood cell, leaving their F C portion exposed with maximal reactivity at 37 °C (versus cold antibody induced hemolytic anemia whose antibodies only bind red blood cells at low body temperatures, typically 28–31 °C).
Acquired hemolytic anemia is also encountered in burns and as a result of certain infections (e.g. malaria). [15] [18] Paroxysmal nocturnal hemoglobinuria (PNH), sometimes referred to as Marchiafava-Micheli syndrome, is a rare, acquired, potentially life-threatening disease of the blood characterized by complement-induced intravascular ...
ABO hemolytic disease of the newborn [1] Anti-Kell hemolytic disease of the newborn [1] Rhesus c hemolytic disease of the newborn [1] Rhesus E hemolytic disease of the newborn [1] Other blood group incompatibility (RhC, Rhe, Kidd, Duffy, MN, P and others) [1] Alloimmune hemolytic blood transfusion reactions (i.e., from a non-compatible blood ...
Drug-induced autoimmune hemolytic anemia: D59.0: Drug-induced autoimmune hemolytic anemia is a type of hemolytic anemia in which a mediated immune response triggers IgG and IgM antibody production in regards to the presence of high doses of penicillin via the hapten mechanism causing the reduction of red blood cells in the spleen. [34]
Paroxysmal cold hemoglobinuria (PCH) or Donath–Landsteiner hemolytic anemia (DLHA) is an autoimmune hemolytic anemia featured by complement-mediated intravascular hemolysis after cold exposure. [1] It can present as an acute non-recurrent postinfectious event in children, or chronic relapsing episodes in adults with hematological malignancies ...
Drug-induced immune hemolytic anemia [2]: ... Splenectomy is usually ineffective for the treatment of cold agglutinin disease because the liver is the predominant ...