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[1] [2] It contains the three antibiotics neomycin, polymyxin B, and bacitracin. [1] It is for topical use. [3] [4] Possible side effects include itchiness and skin rash, [5] and in rare cases hearing loss. [5] It is relatively broad spectrum, being effective against both Gram-negative and Gram-positive bacteria. [2]
Meta-analyses have concluded that probiotics may protect against antibiotic-associated diarrhea in both children and adults. [2] [3] Evidence is insufficient, however, regarding an effect on rates of C. difficile colitis. [4] The efficacy of probiotic AAD prevention is dependent on the probiotic strain(s) used and on the dosage.
About 1.7 to 5 billion cases of diarrhea occur per year. [2] [5] [11] It is most common in developing countries, where young children get diarrhea on average three times a year. [2] Total deaths from diarrhea are estimated at 1.53 million in 2019—down from 2.9 million in 1990. [4]
A study conducted first in mice and then in human volunteers suggests that a common antibiotic, neomycin, which is the main active ingredient in Neosporin, may help protect against viral ...
Electrolyte solutions, while not true antidiarrheals, are used to replace lost fluids and salts in acute cases.; Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
Neomycin is an aminoglycoside antibiotic that displays bactericidal activity against Gram-negative aerobic bacilli and some anaerobic bacilli where resistance has not yet arisen.
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