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His trial on a few epilepsy patients in 1921 was the first use of the ketogenic diet as a treatment for epilepsy. [ 10 ] Wilder's colleague, paediatrician Mynie Gustav Peterman , later formulated the classic diet, with a ratio of one gram of protein per kilogram of body weight in children, 10–15 g of carbohydrate per day, and the remainder of ...
During 1924–1925, Peterman reported results from the Mayo Clinic on the effectiveness of the ketogenic diet to treat epilepsy in children. [3] Peterman’s ketogenic diet was described as consisting of "one gram of protein per kilogram of body weight in children, 10–15 g of carbohydrate per day, and the remainder of the calories in fat".
This discovery sparked the introduction of the MCT-ketogenic diet, a modification of the ketogenic diet. In the MCT-ketogenic diet, MCT oil is added to ketogenic meals, [35] which allows the carbohydrate content to be increased. The efficacy of the MCT ketogenic diet does not differ significantly from the classic ketogenic diet; however, not ...
Freeman advocated for the use of two treatments for pediatric epilepsy that had gone unused for decades: the ketogenic diet and the hemispherectomy. The ketogenic diet is a very carefully controlled diet regimen that is high in fat and low in carbohydrates and has been shown to reduce epilepsy symptoms in children. It was developed in 1921 but ...
Russell Morse Wilder Sr. (November 24, 1885 – December 16, 1959) [1] was an American physician, diabetologist, epileptologist, and medical researcher, known as one of the originators of the ketogenic ("classic keto") diet as a therapy for both epilepsy [2] [3] and diabetes. [4] [5] He coined the term "ketogenic diet."
A modified version of a popular low-carbohydrate, high-fat diet which is less restrictive than the ketogenic diet. The low glycemic index treatment (LGIT) is a new dietary therapy currently being studied to treat epilepsy. LGIT attempts to reproduce the positive effects of the ketogenic diet.
The use of a ketogenic diet is recommended for those with intractable epilepsy. [45] A ketogenic diet is a high-fat, low-carbohydrate diet recommended to be followed when appropriate, along with prescribed anticonvulsants. This diet was designed in order to mimic many of the effects that starvation has on the metabolic functioning of the body. [45]
Once diagnosed, a medically supervised ketogenic diet is usually recommended as it can help to control seizures. [21] The ketogentic diet is the current standard of care treatment, with 80% of patients having >90% seizure reduction [13] and improving some movement disorders in approximately two thirds of GLUT1 deficiency patients. [18]