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The KOH test, also known as a potassium hydroxide preparation or KOH prep, is a quick, inexpensive fungal test to differentiate dermatophytes and Candida albicans symptoms from other skin disorders like psoriasis and eczema. [1] Dermatophytes are a type of fungus that invades the top layer of the skin, hair, or nails.
[1] A germ tube test is a diagnostic test in which a sample of fungal spores are suspended in animal serum and examined by microscopy for the detection of any germ tubes. [ 2 ] It is particularly indicated for colonies of white or cream color on fungal culture , where a positive germ tube test is strongly indicative of Candida albicans .
Treatment plans and management vary across taxa because this disease tends to affect each species differently. Antifungal drugs are the first line of defense to kill the agents causing phaeohyphomycosis, but despite the significant progress made in the last two decades and a 30% increase in available antifungal drugs since 2000, many drugs are ...
Direct microscopy with 10% KOH would show small to medium conidia with ectothrix hair invasion. [11] Performing a wet mount would show 'racquet shaped hyphae' with few macro and microconidia. [ 11 ] Histological examination of a diseased hair shows clefts that between the inner root sheath and hair.
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Malassezia furfur is a fungus that lives on the superficial layers of the dermis.It generally exists as a commensal organism forming a natural part of the human skin microbiota, but it can gain pathogenic capabilities when morphing from a yeast to a hyphal form during its life cycle, through unknown molecular changes. [2]
The fungus grows very slowly, forming dark hyphae, which contain chlamydoconidia cells and black colonies when grown on agar. Piedraia hortae is a dermatophyte and causes a superficial fungal infection known as black piedra, which causes the formation of black nodules on the hair shaft and leads to progressive weakening of the hair. [ 3 ]
About 112 g of KOH dissolve in 100 mL water at room temperature, which contrasts with 100 g/100 mL for NaOH. [14] Thus on a molar basis, KOH is slightly more soluble than NaOH. Lower molecular-weight alcohols such as methanol, ethanol, and propanols are also excellent solvents. They participate in an acid-base equilibrium.