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The dry granulation process is used to form granules without a liquid solution because the product granulated may be sensitive to moisture and heat. Forming granules without moisture requires compacting and densifying the powders. In this process the primary powder particles are aggregated under high pressure.
Controlled particle size distribution of dry granulation or mix to promote better flow of mixture in tablet machine; Improved flow properties of raw materials; Improved colour and/or active ingredient dispersion in tablet excipients; Uniformly sized wet granulation to promote uniform drying
Pharmaceutical manufacturing is the process of industrial-scale synthesis of pharmaceutical drugs as part of the pharmaceutical industry. The process of drug manufacturing can be broken down into a series of unit operations, such as milling, granulation, coating, tablet pressing, and others.
A sieve analysis (or gradation test) is a practice or procedure used in geology, civil engineering, [1] and chemical engineering [2] to assess the particle size distribution (also called gradation) of a granular material by allowing the material to pass through a series of sieves of progressively smaller mesh size and weighing the amount of material that is stopped by each sieve as a fraction ...
Samples of "ground granulated blast furnace slag" (left) and "granulated blast furnace slag" (right) Ground granulated blast-furnace slag (GGBS or GGBFS) is obtained by quenching molten iron slag (a by-product of iron and steel-making) from a blast furnace in water or steam, to produce a glassy, granular product that is then dried and ground into a fine powder.
Wet agglomeration is a process that introduces a liquid binder to develop adhesion forces between the dry particles to be agglomerated. Mixing disperses the liquid over the particles evenly and promotes growth of the aggregate to the desired size. A final drying step is required to stabilize the agglomerates. [1]