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Current recommendations are for a 2-month drug holiday prior to dental surgery for those who are at risk (intravenous drug therapy, greater than 4 years of by-mouth drug therapy, other factors that increase risk such as steroid therapy). [7] It usually develops after dental treatments involving exposure of bone or trauma, but may arise ...
Fosamax is a brand name of the generic drug alendronate. It helps treat osteoporosis due to menopause or steroid use. It works by altering bone formation and the breakdown of the bones in the body.
Alendronic acid, sold under the brand name Fosamax among others, is a bisphosphonate medication used to treat osteoporosis and Paget's disease of bone. [4] It is taken by mouth. [ 4 ] Use is often recommended together with vitamin D , calcium supplementation , and lifestyle changes.
Alendronic acid/colecalciferol, sold under the brand name Fosamax Plus D among others, is a medication for the treatment of osteoporosis in men or in postmenopausal women. [ 3 ] [ 2 ] [ 4 ] [ 6 ] Alendronic acid/colecalciferol was approved for use in the United States and in the European Union in 2005.
About 10 million people age 50 years and older in the U.S. have osteoporosis, a disease that weakens bones, causing them to more easily break. While the majority are women, about 2 million are men.
[3] [4] Risedronate has also been shown to reduce the risk of hip fractures. [5] [6] After five years of medications by mouth or three years of intravenous medication among those at low risk, bisphosphonate treatment can be stopped. [13] In those at higher risk ten years of medication by mouth or six years of intravenous treatment may be used. [13]
The upper limit per day for everyone over 9 years old is 4000 IUs, unless you’ve been screened by your doctor and have issues specific to you that they feel require a higher dose.
The metabolites of raloxifene include several glucuronides. [3] The elimination half-life of raloxifene after a single dose is 27.7 hours (1.2 days), whereas its half-life at steady state at a dosage of 60 mg/day is 15.8 to 86.6 hours (0.7–3.6 days), with an average of 32.5 hours (1.4 days).