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  2. L-DOPA - Wikipedia

    en.wikipedia.org/wiki/L-DOPA

    l-DOPA, also known as l-3,4-dihydroxyphenylalanine and used medically as levodopa, is made and used as part of the normal biology of some plants [2] and animals, including humans. Humans, as well as a portion of the other animals that utilize l -DOPA, make it via biosynthesis from the amino acid l -tyrosine .

  3. Levodopa - Wikipedia

    en.wikipedia.org/wiki/Levodopa

    Levodopa is available, alone and/or in combination with carbidopa, in the form of immediate-release oral tablets and capsules, extended-release oral tablets and capsules, orally disintegrating tablets, as a powder for inhalation, and as an enteral suspension or gel (via intestinal tube).

  4. Dihydroxyphenylalanine - Wikipedia

    en.wikipedia.org/wiki/Dihydroxyphenylalanine

    Dihydroxyphenylalanine may refer to either of two chemical compounds: D -DOPA (R), 3,4-dihydroxyphenylalanine L -DOPA (S), 3,4-dihydroxyphenylalanine, a precursor of a neurotransmitter

  5. Droxidopa - Wikipedia

    en.wikipedia.org/wiki/Droxidopa

    Droxidopa, also known as (–)-threo-3-(3,4-dihydroxyphenyl)-L-serine (L-DOPS), is a substituted phenethylamine and is chemically analogous to levodopa (L-3,4-dihydroxyphenylalanine; L-DOPA). Whereas levodopa functions as a precursor and prodrug to dopamine, droxidopa is a precursor and prodrug of norepinephrine. [citation needed]

  6. D-DOPA - Wikipedia

    en.wikipedia.org/wiki/D-DOPA

    d-DOPA (D-3,4-dihydroxyphenylalanine; dextrodopa) is similar to L-DOPA (levodopa), but with opposite chirality. Levo- and dextro- rotation refer to a molecule's ability to rotate planes of polarized light in one or the other direction.

  7. Tyrosine hydroxylase - Wikipedia

    en.wikipedia.org/wiki/Tyrosine_hydroxylase

    Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). [5] [6] It does so using molecular oxygen (O 2), as well as iron (Fe 2+) and tetrahydrobiopterin as cofactors.

  8. Dopamine - Wikipedia

    en.wikipedia.org/wiki/Dopamine

    The melanin that darkens human skin is not of this type: it is synthesized by a pathway that uses L-DOPA as a precursor but not dopamine. [150] However, there is substantial evidence that the neuromelanin that gives a dark color to the brain's substantia nigra is at least in part dopamine-melanin.

  9. Dihydroxyphenylalanine transaminase - Wikipedia

    en.wikipedia.org/wiki/Dihydroxyphenylalanine...

    The systematic name of this enzyme class is 3,4-dihydroxy-L-phenylalanine:2-oxoglutarate aminotransferase. Other names in common use include dopa transaminase , dihydroxyphenylalanine aminotransferase , aspartate-DOPP transaminase (ADT) , L-dopa transaminase , dopa aminotransferase , glutamate-DOPP transaminase (GDT) , phenylalanine-DOPP ...