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Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. [6] It is recommended to be used together with dietary changes, exercise, and weight loss. [ 6 ]
Cardiovascular agents are drugs that affect the rate and intensity of cardiac contraction, blood vessel diameters, blood volume, blood clotting and blood cholesterol levels. [1] They are indicated to treat diseases related to the heart or the vascular system (blood vessels), such as hypertension , hyperlipidemia , coagulation disorders , heart ...
[21] [22] [23] Risk factors for coronary heart disease included abnormal lipid levels in the blood, diabetes mellitus, high blood pressure, and smoking. [22] They recommended selective use of low-to-moderate doses statins in the same adults who have a calculated 10-year cardiovascular disease event risk of 7.5–10% or greater. [22]
Your doctor may screen you for atherosclerosis during a general check-up or order tests if they suspect you might have a problem with your heart or blood vessels. Initial tests usually include:
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Atherosclerosis generally starts when a person is young and worsens with age. Women are 78% at higher risk level than men [2] Almost all people are affected to some degree by the age of 65. [7] It is the number one cause of death and disability in developed countries.
JUPITER was a randomized double-blind placebo-controlled study investigating the use of rosuvastatin in the primary prevention of cardiovascular disease.The trial focused on patients with normal low-density lipoprotein (LDL) cholesterol levels but increased levels of high-sensitivity C-reactive protein (hs-CRP).
Recent research indicates that three key blood biomarkers can help predict a woman's risk of major cardiovascular events, such as heart attacks and stroke. 3 blood biomarkers predict higher risk ...