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The bromelain gel is contraindicated in persons allergic to pineapple or the enzyme papain. [3] The most common side-effects are fever (19% of patients in studies) and local pain (3.6%). Wound infections occur no more frequently than under standard treatment. [3]
The hormonal effects of quercetin found in animal studies raise the suspicion of a parallel effect in humans, particularly in respect of estrogen-dependent tumors. [38] Quercetin supplementation can interfere with the effects of medications. The precise nature of this interaction is known for some common medicines, but for many, it is not. [38]
Bromelain extract is a mixture of protein-digesting (proteolytic) enzymes and several other substances in smaller quantities. The proteolytic enzymes are sulfhydryl proteases; a free sulfhydryl group of a cysteine amino acid side chain is required for function. The two main enzymes are: Stem bromelain – EC 3.4.22.32; Fruit bromelain – EC 3 ...
Quercetin, specifically, "is found naturally in many healthy, whole foods such as cranberries, dark-colored grapes, garlic, and apples if you eat the skins," says Millstine; with capers and red ...
"Potentiates digitalis activity, increases coronary dilation effects of theophylline, caffeine, papaverine, sodium nitrate, adenosine and epinephrine, increase barbiturate-induced sleeping times" [3] Horse chestnut: conker tree, conker Aesculus hippocastanum: Liver toxicity, allergic reaction, anaphylaxis [3] Kava: awa, kava-kava [4] Piper ...
Bromelain is a protease usually obtained from pineapple stem tissue, which has been medically used for its anti-inflammatory effects (see Bromelain - medical uses). Serratia E-15 protease (also known as serratiopeptidase [13] or serrapeptidase [16]) is another protease that has been proposed as an anti-inflammatory agent. [17]