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Zinc pyrithione (or pyrithione zinc) is a coordination complex of zinc. It has fungistatic (inhibiting the division of fungal cells) and bacteriostatic (inhibiting bacterial cell division) properties and is used in the treatment of seborrhoeic dermatitis [ 2 ] and dandruff .
Like selenium sulfide, zinc pyrithione (a zinc complex with two chelating pyrithione anions) also reduces epidermal turnover and inhibits fungal growth. [3] [unreliable medical source?] It is often administered with ketoconazole for better results. The symptoms do not resolve completely even after prolonged medication.
Regular use of an over-the-counter or prescription antifungal shampoo or cream is a common treatment. The topical antifungal medications ketoconazole and ciclopirox have the best evidence. [10] Ketoconazole should be used twice per week. [8] Shampoo or soap containing zinc pyrithione or selenium disulfide is also used. [8]
Treatment options: There are prescription and OTC medications, such as 5% Benzyl alcohol lotion. Medicated shampoos and special combs can help rid the hair of eggs and bugs as well.
Over-the-counter and prescription antifungal dandruff shampoos are especially helpful, says Dr. Woolery-Lloyd. Try looking for ingredients like zinc pyrithione, selenium sulfide, ketoconazole, or ...
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. [2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff. [2]
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