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Microbial biodegradation is the use of bioremediation and biotransformation methods to harness the naturally occurring ability of microbial xenobiotic metabolism to degrade, transform or accumulate environmental pollutants, including hydrocarbons (e.g. oil), polychlorinated biphenyls (PCBs), polyaromatic hydrocarbons (PAHs), heterocyclic compounds (such as pyridine or quinoline ...
Biodegradation into carbon dioxide and water. Undergo some form of degradation and form metabolites. Persist in the environment unmodified. The amount of the compound that is broken down depends on several factors such as bioavailability and compound structure among many others.
Xenobiotic metabolism (from the Greek xenos "stranger" and biotic "related to living beings") is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as drugs and poisons.
The term xenobiotic is also used to refer to organs transplanted from one species to another. For example, some researchers hope that hearts and other organs could be transplanted from pigs to humans. Many people die every year whose lives could have been saved if a critical organ had been available for transplant.
Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems. More generally, xenobiotic metabolism (from the Greek xenos "stranger" and biotic "related to living beings") is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as any drug ...
The University of Minnesota Biocatalysis and Biodegradation Database (UM-BBD), which contains information on microbial biocatalytic reactions and biodegradation pathways for primarily xenobiotic, chemical compounds. One of its many features allows the prediction of microbial catabolic reactions using substructure searching, a rule-base, and ...
The degradation rate of many organic compounds is limited by their bioavailability, which is the rate at which a substance is absorbed into a system or made available at the site of physiological activity, [11] as compounds must be released into solution before organisms can degrade them. The rate of biodegradation can be measured in a number ...
Biotransformation is the biochemical modification of one chemical compound or a mixture of chemical compounds. Biotransformations can be conducted with whole cells, their lysates, or purified enzymes. [1]