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Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. [1] Professor Marshall Urist and Professor Hari Reddi discovered their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body.
651 110075 Ensembl ENSG00000152785 ENSMUSG00000029335 UniProt P12645 Q8BHE5 RefSeq (mRNA) NM_001201 NM_173404 NM_001310677 RefSeq (protein) NP_001192 NP_001297606 NP_775580 Location (UCSC) Chr 4: 81.03 – 81.06 Mb Chr 5: 99 – 99.03 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bone morphogenetic protein 3, also known as osteogenin, is a protein in humans that is encoded by the ...
12156 Ensembl ENSG00000125845 ENSMUSG00000027358 UniProt P12643 P21274 RefSeq (mRNA) NM_001200 NM_007553 RefSeq (protein) NP_001191 NP_031579 Location (UCSC) Chr 20: 6.77 – 6.78 Mb Chr 2: 133.39 – 133.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bone morphogenetic protein 2 or BMP-2 belongs to the TGF-β superfamily of proteins. Function BMP-2 like other bone morphogenetic ...
655 12162 Ensembl ENSG00000101144 ENSMUSG00000008999 UniProt P18075 P23359 RefSeq (mRNA) NM_001719 NM_007557 RefSeq (protein) NP_001710 NP_001710.1 NP_031583 Location (UCSC) Chr 20: 57.17 – 57.27 Mb Chr 2: 172.71 – 172.78 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bone morphogenetic protein 7 or BMP7 (also known as osteogenic protein-1 or OP-1) is a protein that in humans is ...
2658 12165 Ensembl ENSG00000263761 ENSMUSG00000072625 UniProt Q9UK05 Q9WV56 RefSeq (mRNA) NM_016204 NM_019506 RefSeq (protein) NP_057288 NP_062379 Location (UCSC) Chr 10: 47.32 – 47.33 Mb Chr 14: 33.66 – 33.67 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a protein that in humans is ...
A bone growth factor is a growth factor that stimulates the growth of bone tissue. [1] [2]Known bone growth factors include insulin-like growth factor-1 (IGF-1), insulin-like growth factor-2 (IGF-2), transforming growth factor beta (TGF-β), fibroblast growth factors (FGFs), platelet-derived growth factor (PDGF), parathyroid hormone-related peptide (PTHrP), bone morphogenetic proteins (BMPs ...
Bone morphogenetic protein 8B is a protein that in humans is encoded by the BMP8B gene. [5] [6] [7]The protein encoded by this gene is a member of the TGF-β superfamily. It has close sequence homology to BMP7 and BMP5 and is believed to play a role in bone and cartilage development.
Bone morphogenetic protein 4 is a protein that in humans is encoded by BMP4 gene. [4] [5] BMP4 is found on chromosome 14q22-q23. BMP4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. BMP4 is highly ...