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Micrograph showing apocrine metaplasia of the breast with typical features, [4] including apical snouts with eosinophilic granules. H&E stain. Apocrine metaplasia is a reversible transformation of cells to an apocrine phenotype. It is common in the breast in the context of fibrocystic change. It is seen in women mostly over the age of 50 years.
Micrograph showing apocrine-type metaplasia of the breast with typical oncocytes. [2] H&E stain. Oncocytes (left of image), as seen in a renal oncocytoma. H&E stain. An oncocyte is an epithelial cell characterized by an excessive number of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. Oncocytes can be benign or malignant.
Micrograph showing apocrine metaplasia of the breast with typical features [3] H&E stain. Barrett's esophagus is an abnormal change in the cells of the lower esophagus, thought to be caused by damage from chronic stomach acid exposure. The following table lists some common tissues susceptible to metaplasia, and the stimuli that can cause the ...
The lesions must also show that tumor cells have broken through their ducts of origin to invade adjacent tissue in at least one area. Most of the tumor cells (termed type A cells [15]) typically appear somewhat more irregular than normal apocrine gland cells.
Apocrine metaplasia. Pathology Outlines. Last author update: 28 May 2020; Author: Mikael Häggström, M.D. Author info - Reusing images - Conflicts of interest:
Micrograph showing apocrine metaplasia of the breast with typical features [5] H&E stain. The exact mechanism of the condition is not fully understood, though it is known to be tied to hormone level fluctuation; the condition usually subsides after menopause and is closely related to the menstrual cycle.
Epithelial cells come in a variety of shapes that relate to their function in development or physiology. How epithelial cells adopt particular shapes is poorly understood, but it must involve spatial control of the actin cytoskeleton, which is central to cell shape in all plant cells. Apocrine cells, showing apical snouts towards the lumen.
Acrospiromas are a broad class of benign cutaneous adnexal tumors. [1] Cutaneous adnexal tumors are a group of skin tumors consisting of tissues that have differentiated (i.e. matured from stem cells) towards one or more of the four primary adnexal structures found in normal skin: hair follicles, sebaceous sweat glands, apocrine sweat glands, and eccrine sweat glands. [2]