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Doctors, researchers, and patient advocates say the U.S. could be doing far more to combat Chagas, which causes serious heart disease in an estimated 30% of infected people and can also lead to ...
In many cases the first sign of Chagas heart disease is heart failure, thromboembolism, or chest pain associated with abnormalities in the microvasculature. [18] Also common in chronic Chagas disease is damage to the digestive system, which affects 10–21% of people. [2] Enlargement of the esophagus or colon are the most common digestive ...
As a result, all papayas sold before July 23, 2011, were voluntarily recalled by Agromod. The cases were reported between January 1 and July 18 in 23 states. More than half of the cases were women, with ages ranging from 1 to 91 and an average age of 20; Texas had the most cases with 25 people falling ill.
Chagas disease, caused by a parasite, affects people primarily in rural Latin America. But an estimated 300,000 people in the U.S. have it and many are unaware.
Chagas disease: Carlos Chagas: infectious disease, tropical medicine heart failure Heart failure, enlarged esophagus, enlarged colon: Charcot's triad: Jean-Martin Charcot: surgery: ascending cholangitis: jaundice, fever and chills, RUQ pain Charcot's triad: Jean-Martin Charcot: neurology: multiple sclerosis: nystagmus, intention tremor ...
To complete his work on the pathology of the new disease, Chagas described 27 cases of the acute form of the disease and performed more than 100 autopsies on patients who exhibited the chronic form. Chagas's description of the new disease was to become a classic in medicine, and brought him domestic and international distinction.
Given the 100 million people at risk and Chagas disease's disease burden, funding for R&D to improve treatments is extremely low, making it one of the most neglected of the neglected diseases. In 2007, less than US$1 million (0.04% of R&D funding dedicated to neglected diseases) was spent on the development of new drugs for Chagas disease. [7] [8]
However, only 1.5 million people are estimated to live in areas at moderate or high risk, [1] and for over 20 years the number of cases has been going down due to systematic surveillance and control efforts: in 1998 almost 40,000 cases were reported but almost 300,000 cases were suspected to have occurred; [2] in 2009, the number dropped below ...