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Irritable bowel syndrome, or IBS, is among the most common gastrointestinal conditions today. It affects some 10% to 15% of people in the U.S., per the American College of Gastroenterology. A ...
“A doctor might recommend Tylenol over ibuprofen for patients who need pain relief but cannot tolerate NSAIDs due to stomach issues, risk of bleeding, or cardiovascular concerns,” says Walia ...
While the causes of IBS are still unknown, it is believed that the entire gut–brain axis is affected. [30] [31] Recent findings suggest that an allergy triggered peripheral immune mechanism may underlie the symptoms associated with abdominal pain in patients with irritable bowel syndrome. [32] IBS is more prevalent in obese patients. [33]
As with other NSAIDs, ibuprofen has been reported to be a photosensitizing agent, [38] but it is considered a weak photosensitizing agent compared to other members of the 2-arylpropionic acid class. Like other NSAIDs, ibuprofen is an extremely rare cause of the autoimmune diseases Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis.
The most common symptom associated with bloating is a sensation that the abdomen is full or distended. Rarely, bloating may be painful or cause shortness of breath. [citation needed] Pains that are due to bloating will feel sharp and cause the stomach to cramp. These pains may occur anywhere in the body and can change locations quickly. [8]
Long-term use of NSAIDs can cause gastric erosions, which can become stomach ulcers and in extreme cases can cause severe haemorrhage, resulting in death. The risk of death as a result of GI bleeding caused by the use of NSAIDs is 1 in 12,000 for adults aged 16–45. [5] The risk increases almost twentyfold for those over 75. [5]
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