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Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [8] [9] [10] For acne, it is applied to the skin as a cream, gel or ointment. [10]
Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, and lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [6]
The acquisition included the products Retin-A Micro, Ertaczo, and Renova, also known as tretinoin. [24] In August 2011, Valeant acquired 87.2% of the outstanding shares of Sanitas Group for €314 million. [ 25 ]
The national debate over the rising cost of prescription medicines drew attention to the huge backlog of generic drug applications at the US Food and Drug Administration (FDA). [84] Usually, when enough generic drug products are introduced to the market, the cost to buy prescription medications decreases for both the insurer and the patient.
Trifarotene is a prescription retinoid for the topical treatment acne vulgaris. [14] It functions as a retinoic acid receptor (RAR)-γ agonist. [92] Non-prescription topical products that have health claims for reducing facial acne, combating skin dark spots and reducing wrinkles and lines associated with aging often contain retinyl palmitate.
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