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  2. Drug-induced lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Drug-induced_lupus_erythe...

    Furthermore, anti-histone antibodies can also be positive in drug-induced lupus. [citation needed] Anti-Histone antibodies are positive in up to 95% of patients with drug induced lupus. The most common medications associated with drug induced lupus are hydralazine, procainamide, isoniazid, methyldopa, chlorpromazine, quinidine, and minocycline. [9]

  3. Anti-histone antibodies - Wikipedia

    en.wikipedia.org/wiki/Anti-histone_antibodies

    Patients with drug-induced lupus erythematosus typically have positive tests for anti-histone antibodies but do not have indications for anti-dsDNA antibodies. Patients with idiopathic systemic lupus erythematosus have both types of autoantibodies present in their blood. Thus, this test can be useful in distinguishing these two illnesses. [9]

  4. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    Hydroxychloroquine was approved by the FDA for lupus in 1955. [120] Some drugs approved for other diseases are used for SLE 'off-label'. In November 2010, an FDA advisory panel recommended approving belimumab (Benlysta) as a treatment for the pain and flare-ups common in lupus. The drug was approved by the FDA in March 2011. [121] [122]

  5. Lupus anticoagulant - Wikipedia

    en.wikipedia.org/wiki/Lupus_anticoagulant

    A ratio of 1.2 is commonly used, such that a value <1.2 indicates the absence of a lupus anticoagulant, while a value >1.2 indicates the presence of a lupus anticoagulant. [19] Direct oral anticoagulants and vitamin K antagonists used to treat thrombosis can interfere with lupus anticoagulant assays and generate either false-positive or false ...

  6. Lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Lupus_erythematosus

    Lupus erythematosus may manifest as systemic disease or in a purely cutaneous form also known as incomplete lupus erythematosus. Lupus has four main types: [citation needed] systemic; discoid; drug-induced; neonatal; Of these, systemic lupus erythematosus (also known as SLE) is the most common and serious form.

  7. Childhood-onset systemic lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Childhood-onset_systemic...

    [65] [74] Studies have shown that these drugs help suppress lupus nephritis in adults when combined with other drugs. For example, a regimen consisting of tacrolimus (4 mg per day), mycophenolate mofetil, and a glucocorticoid had a significantly higher response rate in treating adult lupus nephritis than a standard treatment regimen consisting ...

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