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[21] [22] [23] Moreover, high-potency glucocorticoid should be applied to skin only once a day and should not be used for more than fourteen days. [24] Even low-potency topical glucocorticoids are able to cause adverse effects in children when used for prolonged periods of time.
The strength of topical hydrocortisone products ranges from 0.1% to 2.5%, which means there could be 1 mg to 25 mg hydrocortisone in 1g of the products. [12] Some formulations for topical hydrocortisone include hydrocortisone 0.5% cream or ointment, hydrocortisone 1% cream or ointment, and hydrocortisone 2.5% cream or ointment. [34]
Some recommend using the topical steroid for 3 consecutive days on, followed by 4 consecutive days off. [10] Long-term use of topical steroids can lead to secondary infection with fungus or bacteria (see tinea incognito ), skin atrophy, telangiectasia (prominent blood vessels), skin bruising and fragility.
Hydrocortisone aceponate is a veterinary corticosteroid that is used in form of creams for the treatment of various dermatoses (skin conditions). [6] It is an ester of hydrocortisone (cortisol) with acetic acid and propionic acid .
Pyrethrin based flea treatments meant for dogs can be hazardous to cats. Flea and tick ointment is also hazardous to humans. If the product comes into contact with human skin, it is recommended to wash thoroughly with soap and water. [3]
Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons , waxes , or polyethylene glycols as the vehicle for external skin application. [ 1 ]