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Gemfibrozil, sold under the brand name Lopid among others, is a medication used to treat abnormal blood lipid levels. [3] It is generally less preferred than statins . [ 3 ] [ 4 ] Use is recommended together with dietary changes and exercise. [ 3 ]
Elagolix is used in the treatment of moderate to severe pain associated with endometriosis in premenopausal women. [1] Endometriosis is a condition in which the endometrium, the inner lining of the uterus, grows outside of the uterus into surrounding tissues and causes symptoms such as pelvic pain and infertility. [13]
Gemfibrozil, an oral drug used to lower lipid levels; Nardosinone, a sesquiterpene; Octyl salicylate, an ingredient in sunscreens; Sterpuric acid, a sesquiterpene;
The strengths of the available cerivastatin medicine ranged from 0.2 - 0.8 mg, resulting in an actual dose of 1.9 - 13.1 μg/kg body weight for which rhabdomyolysis has been reported. [14] Although the mechanism of the cerivastatin induced myopathy is not exactly known, [ 15 ] the risk increases with statin dose.
Mirabegron, sold under the brand name Myrbetriq among others, is a medication used to treat overactive bladder. [5] Its benefits are similar to antimuscarinic medication such as solifenacin or tolterodine. [6]
Pregnant rats were given very high daily oral doses of vibegron during the period of organogenesis and showed no embryo-fetal developmental toxicity up to 300 mg/kg/day. Similar data was found in rabbits. Maternal toxicity was observed when doses exceeded 100 mg/kg/day in lactating rats.