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Ziconotide, sold under the brand name Prialt, also called intrathecal ziconotide (ITZ) because of its administration route, is an atypical analgesic agent for the amelioration of severe and chronic pain. Derived from Conus magus, a cone snail, it is the synthetic form of an ω-conotoxin peptide. [2]
Shirley A. Pomponi is an American marine biologist who studies sea sponges. Pomponi found a Discodermia dissoluta specimen in 1987, and a compound from it was used as a cancer drug.
This multi-page article lists pharmaceutical drugs alphabetically by name. Many drugs have more than one name and, therefore, the same drug may be listed more than once. ...
One of dozens of toxins made by the deadly cone snail Conus geographus is used as Prialt in pain relief. [44] Since classical times and possibly much earlier, hundreds of species of plants have provided drugs to treat a wide range of conditions.
Conotoxins are hypervariable even within the same species. They do not act within a body where they are produced (endogenously) but act on other organisms. [6]Therefore, conotoxin genes experience less selection against mutations (like gene duplication and nonsynonymous substitution), and mutations remain in the genome longer, allowing more time for potentially beneficial novel functions to ...
Jazz Pharmaceuticals plc (a merger of Jazz Pharmaceuticals, Inc. and Azur Pharma plc) is a global biopharmaceutical company with a focus on oncology and neuroscience.It was founded in 2003 in California, United States. [2]
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Halichondria produces the eribulin (Halaven) precursor halichondrin B. Marine pharmacognosy is the investigation and identification of medically important plants and animals in the marine environment.