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Fenticonazole is an imidazole antifungal drug, used locally as the nitrate in the treatment of vulvovaginal candidiasis. It is active against a range of organisms including dermatophyte pathogens, Malassezia furfur, and Candida albicans.
Clotrimazole is usually used five times daily for 14 days for oral thrush, twice daily for 2 to 8 weeks for skin infections, and once daily for 3 or 7 days for vaginal infections. [ 10 ] Clotrimazole may be compounded with a glucocorticoid , such as betamethasone , in a topical cream for the treatment of tinea corporis (ringworm), tinea cruris ...
Nystatin is used topically for the treatment of Candida infections of the skin and mucous membranes. [9] Oral candidiasis (Oral Thrush) Nystatin is commonly used in treatment of lesions of the mouth caused by oral candidiasis. The drug can be formulated in pastilles or suspensions and is directly applied to the affected area. After application ...
The prevention of Candida infections in people with weak immune systems, such as those neutropenic due to cancer chemotherapy, those with advanced HIV infections, transplant patients, and premature infants. As a second-line agent for the treatment of cryptococcal meningoencephalitis, a fungal infection of the central nervous system.
Some fungi (e.g. Candida krusei and fluconazole) exhibit intrinsic resistance to certain antifungal drugs or classes, whereas some species develop antifungal resistance to external pressures. Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical antifungals ...
It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. [1] It may also be used to prevent candidiasis in those who are at high risk. [1] Nystatin may be used by mouth, in the vagina, or applied to the skin. [1]
Terconazole was the first triazole-based antifungal drug synthesized for human use. Janssen Pharmaceutica developed it in 1983. [21] Previously, all triazole based drugs targeted fungal infections related to plants from Candida species.
Ibrexafungerp, sold under the brand name Brexafemme, is an antifungal medication used to treat vulvovaginal candidiasis (VVC) (vaginal yeast infection). [1] It is taken orally (by mouth). [1] It is also currently undergoing clinical trials for other indications via an intravenous (IV) formulation. An estimated 75% of women will have at least ...