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A chondroprotective compound is a specific compound or chemical that delays progressive joint space narrowing characteristic of arthritis and improves the biomechanics of articular joints by protecting chondrocytes. [1] These agents perform various functions, such as: Stimulating chondrocyte synthesis of collagen and proteoglycans
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. [1] It typically results in warm, swollen, and painful joints. [1] Pain and stiffness often worsen following rest. [1]
In osteoarthritis, joint injection of glucocorticoids (such as hydrocortisone) leads to short term pain relief that may last between a few weeks and a few months. [5] Injections of hyaluronic acid have not produced improvement compared to placebo for knee arthritis, [6] [7] but did increase risk of further pain. [6]
One 2019 study of nearly 1,500 patients with rheumatoid arthritis found that those who took omega-3 supplements self-reported less joint pain and swelling. Yet, walnuts are a good source of omega ...
Osteoarthritis is the most common form of arthritis affecting more than 3.8% of people, while rheumatoid arthritis is the second most common affecting about 0.24% of people. [10] In Australia about 15% of people are affected by arthritis, [ 11 ] while in the United States more than 20% have a type of arthritis. [ 3 ]
The joint space equals the distance between the involved bones of the joint. A joint space narrowing is a sign of either (or both) osteoarthritis and inflammatory degeneration. [12] The normal joint space is at least 2 mm in the hip (at the superior acetabulum), [13] at least 3 mm in the knee, [14] and 4–5 mm in the shoulder joint. [15]