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The complications of diabetes can dramatically impair quality of life and cause long-lasting disability. Overall, complications are far less common and less severe in people with well-controlled blood sugar levels. [3] [4] [5] Some non-modifiable risk factors such as age at diabetes onset, type of diabetes, gender, and genetics may influence risk.
Non-freezing cold injuries (NFCI) is a class of tissue damage caused by sustained exposure to low temperature without actual freezing. [1] There are several forms of NFCI, and the common names may refer to the circumstances in which they commonly occur or were first described, such as trench foot, which was named after its association with trench warfare.
The risk of infection is increased with traumatic injury to the skin and also in people with certain underlying conditions such as diabetes, chronic venous insufficiency and immunosuppression. [3] Staphylococcal and Streptococcal organisms remain the most common causes of superficial infection after a flooding event. [4]
Cold injury (or cold weather injury) is damage to the body from cold exposure, including hypothermia and several skin injuries. [6] Cold-related skin injuries are categorized into freezing and nonfreezing cold injuries. [5] Freezing cold injuries involve tissue damage when exposed to temperatures below freezing (less than 0 degrees Celsius).
A wound is any disruption of or damage to living tissue, such as skin, mucous membranes, or organs. [1] [2] Wounds can either be the sudden result of direct trauma (mechanical, thermal, chemical), or can develop slowly over time due to underlying disease processes such as diabetes mellitus, venous/arterial insufficiency, or immunologic disease. [3]
The pathological mechanism by which frostbite causes body tissue injury can be characterized by four stages: Prefreeze, freeze-thaw, vascular stasis, and the late ischemic stage. [16] Prefreeze phase: involves the cooling of tissues without ice crystal formation. [16] Freeze-thaw phase: ice-crystals form, resulting in cellular damage and death ...
The most frequent cause of hospitalization for diabetic patients is due to foot infections. [3] Symptoms may include pus from a wound, redness, swelling, pain, warmth, tachycardia, or tachypnea. [4] Complications can include infection of the bone, tissue death, amputation, or sepsis. [2] They are common and occur equally frequently in males and ...
Diabetic foot ulcer is a breakdown of the skin and sometimes deeper tissues of the foot that leads to sore formation. It is thought to occur due to abnormal pressure or mechanical stress chronically applied to the foot, usually with concomitant predisposing conditions such as peripheral sensory neuropathy, peripheral motor neuropathy, autonomic neuropathy or peripheral arterial disease. [1]