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The lesions are most frequent on the lower limbs, but may occur anywhere on the body, including the hands, arms, torso and even the neck. They may vary in number and erupt in mass numbers. They consist of irregular patches of orange or brown pigmentation with characteristic "cayenne pepper" spots appearing within and at the edge of old lesions.
This is an accepted version of this page This is the latest accepted revision, reviewed on 11 February 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
Such cells might then aggregate into a spot with an irregular shape. [13] They propose that the protrusion of a flat spot is a result of the death of aged cells in the spot and release of lipofuscin bodies. [13] The aggregating cells would form a capsule, and the dense lipofuscin bodies make the protruding spot soft and dark in color. [13]
Evolution: There are rapid changes to the size, shape or color of a new or existing spot. As melanoma grows, it can also develop itching, bleeding or pain. As melanoma grows, it can also develop ...
Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas. [1]
There are a wide range of depigmenting treatments used for hyperpigmentation conditions, and responses to most are variable. [11]Most often treatment of hyperpigmentation caused by melanin overproduction (such as melasma, acne scarring, liver spots) includes the use of topical depigmenting agents, which vary in their efficacy and safety, as well as in prescription rules.