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Keratoconus (KC) is a disorder of the eye that results in progressive thinning of the cornea. [3] The protrusion of the cornea may result in blurry vision, double vision, nearsightedness, irregular astigmatism, [4] and light sensitivity leading to poor quality-of-life.
Keratoconus, a progressive, noninflammatory, bilateral, asymmetric disease, characterized by paraxial stromal thinning and weakening that leads to corneal surface distortion. [ 2 ] Keratoglobus , a rare noninflammatory corneal thinning disorder, characterised by generalised thinning and globular protrusion of the cornea.
(H18.6) Keratoconus — degenerative disease: the cornea thins and changes shape to be more like a cone than a parabole (H19.3) Keratoconjunctivitis sicca — dry eyes (H20.0) Iritis — inflammation of the iris (H20.0, H44.1) Uveitis — inflammatory process involving the interior of the eye; Sympathetic ophthalmia is a subset.
Another long-term study of 181 patients puts the chances of retaining an intact OOKP after 18 years at 85%. [ 7 ] In 2022, a retrospective study conducted on 82 eyes with OOKP using original Strampelli technique, showed an anatomical survival of 94% up to 30 years of follow-up.
Abnormal corneal topography compromises of keratoconus, pellucid marginal degeneration, or forme fruste keratoconus with an I-S value of 1.4 or more [4] is the most significant risk factor. Low age, low residual stromal bed (RSB) thickness, low preoperative corneal thickness, and high myopia are other important risk factors.
Racial predilections do not exist for this disease. [14] A study based on 274 answers using the Ocular Surface Disease Index (OSDI) from medical school students aged between 20 and 25 years old found a prevalence of dry eye symptoms of 83.6%. [65]
Layers of the Cornea (1) Epithelium (2) Anterior elastic lamina (3) Substantia propria (4) Posterior elastic lamina (5) Endothelium of the anterior chamber Disposable, soft contact lenses. Keratitis, or an inflammation of the cornea. The effects of extended contact lens wear on the cornea have been studied extensively and are well-documented.
Posterior corneal dystrophies – Fuchs corneal dystrophy presents during the fifth or sixth decade of life. The characteristic clinical findings are excrescences on a thickened Descemet membrane (cornea guttae), generalized corneal edema and decreased visual acuity. In advanced cases, abnormalities are found in all the layers of the cornea.