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The link between NSAIDs and hearing loss tends to be greater in women, especially those who take ibuprofen six or more times a week. [36] Others may cause permanent hearing loss. [37] The most important group is the aminoglycosides (main member gentamicin) and platinum based chemotherapeutics such as cisplatin and carboplatin. [38] [39]
Hearing loss is a partial or total inability to hear. [5] Hearing loss may be present at birth or acquired at any time afterwards. [6] [7] Hearing loss may occur in one or both ears. [2] In children, hearing problems can affect the ability to acquire spoken language, and in adults it can create difficulties with social interaction and at work. [8]
A 2020 study suggests that the main cause of presbycusis is the loss of inner ear sensory cellsand that the main cause of this loss is noise exposure. [14] Neural: characterised by degeneration of cells of the spiral ganglion. Strial/metabolic: characterised by atrophy of stria vascularis in all turns of cochlea.
[3] [14] Additionally, hearing loss is not as common as in type 2. [3] Rarely, cleft lip has been reported in this form of Waardenburg syndrome. [15] Type 4 can also be caused by a mutation in SOX10 (the same gene as in type 2E), in which it is known as type 4C; hearing loss is very common and severe in this type. [16]
Prelingual hearing loss can be considered congenital, present at birth, or acquired, occurring after birth before the age of one. Congenital hearing loss can be a result of maternal factors (rubella, cytomegalovirus, or herpes simplex virus, syphilis, diabetes), infections, toxicity (pharmaceutical drugs, alcohol, other drugs), asphyxia, trauma, low birth weight, prematurity, jaundice, and ...
Auditory neuropathy (AN) is a hearing disorder in which the outer hair cells of the cochlea are present and functional, but sound information is not transmitted sufficiently by the auditory nerve to the brain. The cause may be several dysfunctions of the inner hair cells of the cochlea or spiral ganglion neuron levels. [1]
Hearing loss that worsens with age but is caused by factors other than normal aging, such as noise-induced hearing loss, is not presbycusis, although differentiating the individual effects of multiple causes of hearing loss can be difficult. One in three persons have significant hearing loss by age 65; by age 75, one in two.
Spatial hearing loss is found in most people over 70 years of age, and can sometimes be independent of other types of age related hearing loss. [2] As with presbycusis, spatial hearing loss varies with age. Through childhood and into adulthood it can be viewed as spatial hearing gain (with it becoming easier to hear speech in noise), and then ...