Search results
Results From The WOW.Com Content Network
Varicella vaccine, also known as chickenpox vaccine, is a vaccine that protects against chickenpox. [9] One dose of vaccine prevents 95% of moderate disease and 100% of severe disease. [ 10 ] Two doses of vaccine are more effective than one. [ 10 ]
Chickenpox, also known as varicella (/ ˌ v ɛ r ə ˈ s ɛ l ə / VER-ə-SEL-ə), is a highly contagious disease caused by varicella zoster virus (VZV), a member of the herpesvirus family. [ 3 ] [ 7 ] [ 5 ] The disease results in a characteristic skin rash that forms small, itchy blisters , which eventually scab over. [ 1 ]
Varicella zoster virus is not the same as herpes simplex virus, although they both belong to the alpha subfamily of herpesviruses. [14] Shingles vaccines reduce the risk of shingles by 50 to 90%, depending on the vaccine used. [1] [15] Vaccination also decreases rates of postherpetic neuralgia, and, if shingles occurs, its severity. [1]
Herpes virus DNA contains a gene for a protein called ICP4, which is an important transactivator of genes associated with lytic infection in HSV-1. [47] Elements surrounding the gene for ICP4 bind a protein known as the human neuronal protein neuronal restrictive silencing factor (NRSF) or human repressor element silencing transcription factor ...
Schematic drawing of a Herpesviridae virion. All members of the Herpesviridae share a common structure; a relatively large, monopartite, double-stranded, linear DNA genome encoding 100–200 genes encased within an icosahedral protein cage (with T=16 symmetry) called the capsid, which is itself wrapped in a protein layer called the tegument containing both viral proteins and viral mRNAs and a ...
Vaccine Excipients Adenovirus vaccine: This list refers to the type 4 and type 7 adenovirus vaccine tablets licensed in the US: Acetone, alcohol, anhydrous lactose, castor oil, cellulose acetate phthalate, dextrose, D-fructose, D-mannose, FD&C Yellow #6 aluminium lake dye, fetal bovine serum, human serum albumin, magnesium stearate, micro crystalline cellulose, plasdone C, Polacrilin potassium ...
A zoster vaccine is a vaccine that reduces the incidence of herpes zoster (shingles), a disease caused by reactivation of the varicella zoster virus, which is also responsible for chickenpox. [8] Shingles provokes a painful rash with blisters, and can be followed by chronic pain (postherpetic neuralgia), as well as other complications.
Chickenpox-like rashes were recognized and described by ancient civilizations; the relationship between zoster and chickenpox was not realized until 1888. [29] In 1943, the similarity between virus particles isolated from the lesions of zoster and those from chickenpox was noted. [30] In 1974 the first chickenpox vaccine was introduced. [31]