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  2. Dercum's disease - Wikipedia

    en.wikipedia.org/wiki/Dercum's_disease

    Dercum's disease is a rare condition characterized by multiple painful fatty tumors, called lipomas, that can grow anywhere in subcutaneous fat from scalp to plantar surface of the foot. [1] Sometimes referred as adiposis dolorosa in medical literature, Dercum’s disease is more of a syndrome than a disease (because it has several clinically ...

  3. Fatty liver disease - Wikipedia

    en.wikipedia.org/wiki/Fatty_liver_disease

    Fatty liver disease (FLD), also known as hepatic steatosis and steatotic liver disease (SLD), is a condition where excess fat builds up in the liver. [1] Often there are no or few symptoms. [1][2] Occasionally there may be tiredness or pain in the upper right side of the abdomen. [1] Complications may include cirrhosis, liver cancer, and ...

  4. Panniculitis - Wikipedia

    en.wikipedia.org/wiki/Panniculitis

    Panniculitis is a group of diseases whose hallmark is inflammation of subcutaneous adipose tissue (the fatty layer under the skin – panniculus adiposus). [1] Symptoms include tender skin nodules, and systemic signs such as weight loss and fatigue. Restated, an inflammatory disorder primarily localized in the subcutaneous fat is termed a ...

  5. Metabolic dysfunction–associated steatotic liver disease

    en.wikipedia.org/wiki/Metabolic_dysfunction...

    Adipose tissue dysfunction also decreases secretion of the insulin-sensitizing adipokine adiponectin in people with NAFLD. [20] Adiponectin has several properties that protect the liver. [ 20 ] These properties include improved liver fat metabolism, decreased de novo lipogenesis, decreased glucose production in the liver , anti-inflammatory ...

  6. Lipedema - Wikipedia

    en.wikipedia.org/wiki/Lipedema

    Lipedema is a medical condition that is almost exclusively found in women [3] and results in enlargement of both legs due to deposits of fat under the skin. [2] Women of any weight may develop lipedema [2][3] and the fat associated with lipedema is resistant to traditional weight-loss methods. [4] There is no cure and typically it gets worse ...

  7. Adipose tissue - Wikipedia

    en.wikipedia.org/wiki/Adipose_tissue

    Adipose tissue (also known as body fat or simply fat) is a loose connective tissue composed mostly of adipocytes. [ 1 ][ 2 ] It also contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells such as adipose tissue macrophages.

  8. Fat necrosis - Wikipedia

    en.wikipedia.org/wiki/Fat_necrosis

    Fat necrosis may result from various injuries to adipose tissue, including: physical trauma, enzymatic digestion of adipocytes by lipases, [3] radiation therapy, [4] hypoxia, or inflammation of subcutaneous fat (panniculitis). The gross appearance of fat necrosis is as an irregular, chalky white area within otherwise normal adipose tissue. [1]

  9. Pathophysiology of obesity - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_obesity

    Abdominal obesity, excess fat cell accumulation in adipose tissue of the abdomen, is associated more strongly with meta-inflammation. [9] Evolutionarily, adipose tissue has been shown to function as an immune organ. [8] The immune cells located in adipose tissue are important for maintaining metabolic homeostasis.