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The first plague vaccine was developed by bacteriologist Waldemar Haffkine in 1897. [3] [4] He tested the vaccine on himself to prove that the vaccine was safe.[4] [5] Later, Haffkine conducted a massive inoculation program in British India, and it is estimated that 26 million doses of Haffkine's anti-plague vaccine were sent out from Bombay between 1897 and 1925, reducing the plague mortality ...
Symptoms of the Bubonic Plague included painful and enlarged or swollen lymph nodes, headaches, chills, fatigue, vomiting, and fevers, and within 3 to 5 days, 80% of the victims would be dead. [1] Historians estimate that it reduced the total world population from 475 million to between 350 and 375 million.
The plague is considered the likely cause of the Black Death that swept through Asia, Europe, and Africa in the 14th century and killed an estimated 50 million people, [1] [10] including about 25% to 60% of the European population. [1] [11] Because the plague killed so many of the working population, wages rose due to the demand for labor. [11]
Mutations that helped humans survive the bubonic plague are still measurable — and appears to make people more susceptible to some chronic diseases.
25,000,000 – 50,000,000 (estimated) The Black Death was a bubonic plague pandemic occurring in Europe from 1346 to 1353. It was one of the most fatal pandemics in human history; as many as 50 million people [2] perished, perhaps 50% of Europe's 14th century population. [3] The disease is caused by the bacterium Yersinia pestis and spread by ...
Adverse events. According to the U.S. Centers for Disease Control and Prevention, while "any vaccine can cause side effects", [11] most side effects are minor, primarily including sore arms or a mild fever. [11] Unlike most medical interventions vaccines are given to healthy people, where the risk of side effects is not as easily outweighed by ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 18 September 2024. Russian-French microbiologist (1860–1930) Waldemar Mordechai Haffkine Born 15 March 1860 (1860-03-15) Odessa, Kherson Governorate, Russian Empire (now Ukraine) Died 26 October 1930 (1930-10-27) (aged 70) Lausanne, Switzerland Citizenship Russian Empire France (later) British Alma ...
Appearance. Theories of the Black Death are a variety of explanations that have been advanced to explain the nature and transmission of the Black Death (1347–51). A number of epidemiologists from the 1980s to the 2000s challenged the traditional view that the Black Death was caused by plague based on the type and spread of the disease.