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The most commonly used stain in histology is a combination of hematoxylin and eosin (often abbreviated H&E). Hematoxylin is used to stain nuclei blue, while eosin stains the cytoplasm and the extracellular connective tissue matrix of most cells pink. There are hundreds of various other techniques which have been used to selectively stain cells.
Histopathology is the branch of histology that includes the microscopic identification and study of diseased tissue. [ 5 ] [ 6 ] It is an important part of anatomical pathology and surgical pathology , as accurate diagnosis of cancer and other diseases often requires histopathological examination of tissue samples. [ 10 ]
Defining cerebral cytoarchitecture began with the advent of histology—the science of slicing and staining brain slices for examination. [2] It is credited to the Viennese psychiatrist Theodor Meynert (1833–1892), who in 1867 noticed regional variations in the histological structure of different parts of the gray matter in the cerebral hemispheres.
Molecular pathology is an emerging discipline within anatomical and clinical pathology that is focused on the use of nucleic acid-based techniques such as in-situ hybridization, reverse-transcriptase polymerase chain reaction, and nucleic acid microarrays for specialized studies of disease in tissues and cells. Molecular pathology shares some ...
Molecular pathology is focused upon the study and diagnosis of disease through the examination of molecules within organs, tissues or bodily fluids. [21] Molecular pathology is multidisciplinary by nature and shares some aspects of practice with both anatomic pathology and clinical pathology, molecular biology, biochemistry, proteomics and ...
Brain cells make up the functional tissue of the brain. The rest of the brain tissue is the structural stroma that includes connective tissue such as the meninges , blood vessels , and ducts. The two main types of cells in the brain are neurons , also known as nerve cells, and glial cells , also known as neuroglia. [ 1 ]
Oligodendrocytes are a type of glial cell, non-neuronal cells in the central nervous system.They arise during development from oligodendrocyte precursor cells (OPCs), [8] which can be identified by their expression of a number of antigens, including the ganglioside GD3, [9] [10] [11] the NG2 chondroitin sulfate proteoglycan, and the platelet-derived growth factor-alpha receptor subunit (PDGF ...
The cells of meristematic tissue are similar in structure and have a thin and elastic primary cell wall made of cellulose. They are compactly arranged without inter-cellular spaces between them. Each cell contains a dense cytoplasm and a prominent cell nucleus. The dense protoplasm of meristematic cells contains very few vacuoles.