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Periarteriolar lymphoid sheaths (or periarterial lymphatic sheaths, or PALS) are a portion of the white pulp of the spleen.They are populated largely by T cells and surround central arteries within the spleen; the PALS T-cells are presented with blood borne antigens via myeloid dendritic cells.
The cords of Billroth (also known as splenic cords or red pulp cords) are found in the red pulp of the spleen between the sinusoids, consisting of fibrils and connective tissue cells with a large population of monocytes and macrophages.
At left is a micrograph of spleen with hyaline deposition (pink material at top of image) in association with inflammation (hyaloserositis), using H&E stain. At right is a micrograph of a kidney with arterial hyaline (hyaline arteriolosclerosis), using PAS stain.
White pulp is a histological designation for regions of the spleen (named because it appears whiter than the surrounding red pulp on cross section), that encompasses approximately 25% of splenic tissue. White pulp consists entirely of lymphoid tissue.
Micrograph of the spleen showing darkly stained, spheroid Gamna-Gandy bodies (arrows) outside the vessel wall at the center. Also shown is diffusely scattered, brown, granular hemosiderin pigment (arrowheads), indicating previous hemorrhage (hematoxylin & eosin staining, 40x magnification).
Category: Histopathology of chronic venous congestion of liver Chronic venous congestion of spleen: Micrograph showing chronic venous congestion of spleen. Sinusoids are dialated. Organized foci of old hemorrhage seen as areas of fibrosis containing brown pigment (hemosiderin). Category: Histopathology of chronic venous congestion of spleen
White pulp, splenic lymphoid nodules, or white nodules — follicles in the white pulp of the spleen, containing many lymphocytes; These structures are named after Marcello Malpighi (1628–1694), an Italian physician and biologist regarded as the father of microscopical anatomy and histology
The spleen (from Anglo-Norman espleen, ult. from Ancient Greek σπλήν, splḗn) [1] is an organ found in almost all vertebrates. Similar in structure to a large lymph node, it acts primarily as a blood filter. The spleen plays important roles in regard to red blood cells (erythrocytes) and the immune system. [2]