Ads
related to: how b cells recognize and respond to an antigen that causes the rate of change
Search results
Results From The WOW.Com Content Network
The immune system may respond in multiple ways to an antigen; a key feature of this response is the production of antibodies by B cells (or B lymphocytes) involving an arm of the immune system known as humoral immunity. The antibodies are soluble and do not require direct cell-to-cell contact between the pathogen and the B-cell to function.
The most common simplified overview description of the B cell differentiation pathway involves the following steps: an antigen interacts with the corresponding surface membrane immunoglobulin after which the B cell begins expressing receptors for growth factors secreted by T cells (BCGFs and IL-2), after these factors bind, the lymphocytes ...
B cell activation: from immature B cell to plasma cell or memory B cell Basic B cell function: bind to an antigen, receive help from a cognate helper T cell, and differentiate into a plasma cell that secretes large numbers of antibodies. B cell activation occurs in the secondary lymphoid organs (SLOs), such as the spleen and lymph nodes. [1]
A signal transduced by the binding of the peptide to the B cell causes the cells to migrate to the edge of the follicle bordering the T cell area. [5] The B cells internalize the foreign peptides, break them down, and express them on class II major histocompatibility complexes (MHCII), which are cell surface proteins. Within the secondary ...
After the inflammatory immune response to danger-associated antigen, some of the antigen-specific T cells and B cells persist in the body and become long-living memory T and B cells. After the second encounter with the same antigen, they recognize the antigen and mount a faster and more robust response.
Acquired immunity depends upon the interaction between antigens and a group of proteins called antibodies produced by B cells of the blood. There are many antibodies and each is specific for a particular type of antigen. Thus immune response in acquired immunity is due to the precise binding of antigens to antibody.
After activation by antigen, these B cells proliferate. If these activated B cells encounter specific signaling molecules via their CD40 and cytokine receptors (both modulated by T helper cells), they undergo antibody class switching to produce IgG, IgA or IgE antibodies. During class switching, the constant region of the immunoglobulin heavy ...
Priming is the first contact that antigen-specific T helper cell precursors have with an antigen. It is essential to the T helper cells' subsequent interaction with B cells to produce antibodies. [1] Priming of antigen-specific naive lymphocytes occurs when antigen is presented to them in immunogenic form (capable of inducing an immune response).
Ad
related to: how b cells recognize and respond to an antigen that causes the rate of change