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There are a limited number of non-surgical fertility control options available for cats and dogs, which vary in effectiveness, duration of action and safety. Progestin contraceptives are approved for contraception in male and female dogs and cats in multiple countries. Typically approval is for a few months of use.
Xenoestrogens are a type of xenohormone that imitates estrogen.They can be either synthetic or natural chemical compounds.Synthetic xenoestrogens include some widely used industrial compounds, such as PCBs, BPA, and phthalates, which have estrogenic effects on a living organism even though they differ chemically from the estrogenic substances produced internally by the endocrine system of any ...
Xenoestrogens are xenohormones that mimic the effects of natural estrogen. When present in the body, xenoestrogens can bind with estrogen receptors in the brain, leading to a disruption in the gonadal endocrine system. Xenoestrogen exposure during different developmental periods can have differing effects on the reproductive system.
A comparison of the structures of the natural estrogen hormone estradiol (left) and one of the nonyl-phenols (right), a xenoestrogen endocrine disruptor. Endocrine disruptors, sometimes also referred to as hormonally active agents, [1] endocrine disrupting chemicals, [2] or endocrine disrupting compounds [3] are chemicals that can interfere with endocrine (or hormonal) systems. [4]
Bisphenol A is an endocrine disruptor that can mimic estrogen and has been shown to cause negative health effects in animal studies. Bisphenol A closely mimics the structure and function of the hormone estradiol by binding to and activating the same estrogen receptor as the natural hormone.
The most important aspect of treatment of pyometra is quick action to provide supportive care. Female dogs are often septic and in shock (see septic shock). [1] Intravenous fluids and antibiotics should be given immediately. Once the female dog has been stabilized, then the treatment of choice is an emergency spay.
The similarities, at molecular level, of an estrogen and a phytoestrogen allow them to mildly mimic and sometimes act as an antagonist of estrogen. [2] Phytoestrogens were first observed in 1926, [ 2 ] [ 5 ] but it was unknown if they could have any effect in human or animal metabolism.
There is variation between the available methods of cattle estrous synchronization. Treatment depends on herd size, specific goals for control, and budget. [4] Some of the FDA-approved drugs and devices used to mimic natural hormones of the estrous cycle include, but are not limited to, the following classes: