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Amlodipine's safety in pregnancy has not been established, although reproductive toxicity at high doses is known. Whether amlodipine enters the milk of breastfeeding mothers is also unknown. [7] [6] Those who have heart failure, or recently had a heart attack, should take amlodipine with caution. [29]
Here’s what can be confusing about cholesterol: Sometimes high cholesterol is cause for concern and sometimes it isn’t. “Some people with high cholesterol levels never get heart disease ...
Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]
Grade 1 hypertension. The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial, also known as ALLHAT, was a randomized, double-blind, active-controlled study comparing at the same time, four different classes of antihypertensive drugs with the rate of coronary heart disease (CHD) events in ‘high-risk’ people with hypertension. [1]
And if you spend enough time in the borderline category, the effects can add up. People who had borderline high cholesterol for 11 to 20 years had twice as high a risk of developing heart disease ...
Amlodipine/atorvastatin, sold under the brand name Caduet among others, is a fixed-dose combination medication for the treatment of high cholesterol and high blood pressure. It contains a statin and a calcium channel blocker .
High cholesterol is a common problem, but there are some straightforward steps you can take to lower it. (Getty Images) (Ca-ssis via Getty Images) High cholesterol is known as the “silent killer ...
It decreases LDL by 15–30% and raises HDL by 3–5%, with little effect on triglycerides, but can cause a slight increase. Bile acid sequestrants may cause gastrointestinal problems and may also reduce the absorption of other drugs and vitamins from the gut. Ezetimibe is a selective inhibitor of dietary cholesterol absorption.