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Triple-negative is sometimes used as a surrogate term for basal-like. [2] Triple-negative breast cancer comprises 15–20% of all breast cancer cases [3] and affects more young women or women with a mutation in the BRCA1 gene than other breast cancers. [4] Triple-negative breast cancers comprise a very heterogeneous group of cancers.
This is an accepted version of this page This is the latest accepted revision, reviewed on 2 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...
Conversely, triple negative cancer (i.e. no positive receptors), lacking targeted treatments, now has a comparatively poor prognosis. [42] [43] Androgen receptor is expressed in 80-90% of ER+ breast cancers and 40% of "triple negative" breast cancers. Activation of androgen receptors appears to suppress breast cancer growth in ER+ cancer while ...
Mackey's “first ever mammogram,” led to a biopsy that diagnosed her with stage 3 triple negative breast cancer. The mom of two daughters, 3 and 6 at the time, felt ready to act.
Breast cancer is the most common cancer in women worldwide, and can, rarely, also occur in men. There are many different types of breast cancer, of which triple-negative breast cancer is one of ...
The rates of late-stage breast cancer at diagnosis have risen among women in all racial and ethnic groups, ... including a higher rate of triple-negative breast cancers," study co-author, Edward ...
The Triple Negative Breast Cancer Foundation ("TNBC Foundation") is a nonprofit organization dedicated to raising awareness of triple negative breast cancer.The foundation supports scientists and researchers in their efforts to determine the definitive causes of triple negative breast cancer so that effective detection, diagnosis, prevention, and treatment can be pursued and achieved.
That led to a diagnosis of Stage 3 triple-positive, inflammatory breast cancer, "a fairly rare and aggressive subtype," LaScala explains. “At 40, that was young to be diagnosed, and I was ...