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  2. Spinothalamic tract - Wikipedia

    en.wikipedia.org/wiki/Spinothalamic_tract

    This fact aids in determining whether a lesion is in the brain or the spinal cord. With lesions in the brain stem or higher, deficits of pain perception, touch sensation, and proprioception are all contralateral to the lesion. With spinal cord lesions, however, the deficit in pain perception is contralateral to the lesion, whereas the other ...

  3. Intrathecal administration - Wikipedia

    en.wikipedia.org/wiki/Intrathecal_administration

    Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF). It is useful in several applications, such as for spinal anesthesia, chemotherapy, or pain management. This route is also used to introduce drugs that fight ...

  4. Myelitis - Wikipedia

    en.wikipedia.org/wiki/Myelitis

    Myelitis is inflammation of the spinal cord which can disrupt the normal responses from the brain to the rest of the body, and from the rest of the body to the brain. . Inflammation in the spinal cord can cause the myelin and axon to be damaged resulting in symptoms such as paralysis and sen

  5. Neurogenic shock - Wikipedia

    en.wikipedia.org/wiki/Neurogenic_shock

    Neurogenic shock results from damage to the spinal cord above the level of the 6th thoracic vertebra. [5] It is found in about half of people who have a spinal cord injury within the first 24 hours, and usually persists for one to three weeks. [5] Neurogenic shock may be caused by severe brain injury. [6]

  6. Spinal cord - Wikipedia

    en.wikipedia.org/wiki/Spinal_cord

    Sectional organization of spinal cord. The spinal cord is the main pathway for information connecting the brain and peripheral nervous system. [3] [4] Much shorter than its protecting spinal column, the human spinal cord originates in the brainstem, passes through the foramen magnum, and continues through to the conus medullaris near the second lumbar vertebra before terminating in a fibrous ...

  7. Dorsal column–medial lemniscus pathway - Wikipedia

    en.wikipedia.org/wiki/Dorsal_column–medial...

    The action signal will continue along the central axon of the neuron through the posterior root, into the posterior horn, and up the posterior column of the spinal cord. Axons from the lower body enter the posterior column below the level of T6 and travel in the midline section of the column called the gracile fasciculus. [ 5 ]

  8. Somatosensory system - Wikipedia

    en.wikipedia.org/wiki/Somatosensory_system

    All afferent touch/vibration information ascends the spinal cord via the dorsal column-medial lemniscus pathway via gracilis (T7 and below) or cuneatus (T6 and above). Cuneatus sends signals to the cochlear nucleus indirectly via spinal grey matter, this info is used in determining if a perceived sound is just villi noise/irritation.

  9. Central nervous system disease - Wikipedia

    en.wikipedia.org/wiki/Central_nervous_system_disease

    Degenerative spinal disorders involve a loss of function in the spine. Pressure on the spinal cord and nerves may be associated with herniation or disc displacement. Brain degeneration also causes central nervous system diseases (i.e. Alzheimer's, Lewy body dementia, Parkinson's, and Huntington's diseases).