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Famotidine, sold under the brand name Pepcid among others, is a histamine H 2 receptor antagonist medication that decreases stomach acid production. [4] It is used to treat peptic ulcer disease , gastroesophageal reflux disease , and Zollinger-Ellison syndrome . [ 4 ]
Because of its hormonal effects, cimetidine rarely may cause sexual dysfunction including loss of libido and erectile dysfunction and gynecomastia (0.1–0.2%) in males during long-term treatment. [16] [17] [18] Rarely, interstitial nephritis, urticaria, and angioedema have been reported with cimetidine treatment. [16]
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
Can someone more versed on this subject provide more insight into the long-term side-effects of famotidine? The ranitidine article has well documented concerns about liver damage, possibly giving undue weight to the safety of drugs like famotidine, whose article doesn't raise any concerns about long-term side-effects.
The 2020-2025 Dietary Guidelines for Americans suggests that limiting calories to 1,200 per day is too low for most people to meet their nutritional needs, plus it’s unsustainable for long-term ...
How To Pack Homemade Bread for Long-Term Storage. If you want to preserve your homemade bread for a longer period, freezing is the best option. After allowing the bread to cool completely, slice ...