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  2. Contraindication - Wikipedia

    en.wikipedia.org/wiki/Contraindication

    In medicine, a contraindication is a condition (a situation or factor) that serves as a reason not to take a certain medical treatment due to the harm that it would cause the patient. [ 1 ] [ 2 ] Contraindication is the opposite of indication , which is a reason to use a certain treatment.

  3. Drug intolerance - Wikipedia

    en.wikipedia.org/wiki/Drug_intolerance

    Just as different people have different pain tolerances, so too do people have different tolerances for dealing with the adverse effects from their medications. For example, while opioid-induced constipation may be tolerable to some individuals, other people may stop taking an opioid due to the unpleasantness of the constipation even if it ...

  4. Ipratropium bromide - Wikipedia

    en.wikipedia.org/wiki/Ipratropium_bromide

    The main contraindication for ipratropium in any form is hypersensitivity to atropine and related substances. [20] [21]Conditions such as narrow-angle glaucoma, prostatic hyperplasia, or bladder neck obstruction are not necessarily contraindicators, but should be taken into account, particularly if the patient is receiving an anticholinergic by another route.

  5. Indication (medicine) - Wikipedia

    en.wikipedia.org/wiki/Indication_(medicine)

    There can be multiple indications to use a procedure or medication. [2] An indication can commonly be confused with the term diagnosis . A diagnosis is the assessment that a particular medical condition is present while an indication is a reason for use. [ 3 ]

  6. Adverse effect - Wikipedia

    en.wikipedia.org/wiki/Adverse_effect

    Adverse effects, like therapeutic effects of drugs, are a function of dosage or drug levels at the target organs, so they may be avoided or decreased by means of careful and precise pharmacokinetics, the change of drug levels in the organism in function of time after administration. Adverse effects may also be caused by drug interaction. This ...

  7. Adverse drug reaction - Wikipedia

    en.wikipedia.org/wiki/Adverse_drug_reaction

    Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.

  8. Pharmacovigilance - Wikipedia

    en.wikipedia.org/wiki/Pharmacovigilance

    A risk management plan is a documented plan that describes the risks (adverse drug reactions and potential adverse reactions) associated with the use of a drug and how they are being handled (warning on drug label or on packet inserts of possible side effects which if observed should cause the patient to inform/see his physician and/or ...

  9. Adverse event - Wikipedia

    en.wikipedia.org/wiki/Adverse_event

    In pharmaceuticals, an adverse event (AE) is any unexpected or harmful medical occurrence that happens to a patient during medical treatment or a clinical trial. Unlike direct side effects , an adverse event does not necessarily mean the medication directly caused the problem.