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Examples of various lipid species. Lipidomics is the large-scale study of pathways and networks of cellular lipids in biological systems. [1] [2] [3] The word "lipidome" is used to describe the complete lipid profile within a cell, tissue, organism, or ecosystem and is a subset of the "metabolome" which also includes other major classes of biological molecules (such as amino acids, sugars ...
Lipidomics is a research field that studies the pathways and networks of cellular lipids in biological systems (i.e., lipidomes) on a large scale. It involves the identification and quantification of the thousands of cellular lipid molecular species and their interactions with other lipids, proteins, and other moieties in vivo.
LIPID MAPS was founded in 2003 with NIH funding. [14] LIPID MAPS was previously funded by a multi-institutional grant from Wellcome, and is now funded under an MRC Partnership award, held jointly by University of Cardiff led by Prof Valerie O'Donnell, the Babraham Institute, UCSD and Swansea University, and The University of Edinburgh.
Microbiomics is the study of microbiome dynamics, function, and structure. [20] This area of study employs several techniques to study the microbiome in its host environment: [19] Sampling methods focused on collecting representative samples of the local environment, either from oral swabs or stool. [19]
Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism. Specifically, metabolomics is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind", the study of their small-molecule metabolite ...
The PRISMA flow diagram, depicting the flow of information through the different phases of a systematic review. PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) is an evidence-based minimum set of items aimed at helping scientific authors to report a wide array of systematic reviews and meta-analyses, primarily used to assess the benefits and harms of a health care ...
A specific example of this occurred in a study involving colon cancer that resulted in the discovery of potential targets for cancer treatment. [16] Proteogenomics has also led to personalized cancer targeting immunotherapies, where antibody epitopes for cancer antigens are predicted using proteogenomics to create medicines that act on the ...
This method was also used to build a model of the Influenza Virus Infection. Some of the results were not in accordance with earlier research papers and the Boolean network showed that the amount of activated macrophages increased for both young and old mice, while others suggest that there is a decrease.