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Finally, the primate ancestor of HIV-1 group O, a strain infecting 100,000 people mostly from Cameroon but also from neighbouring countries, was confirmed in 2006 to be SIVgor. [8] The pandemic HIV-1 group M is most closely related to the SIVcpz collected from the southeastern rain forests of Cameroon (modern East Province) near the Sangha ...
HIV-1 is more virulent and more infective than HIV-2, [20] and is the cause of the majority of HIV infections globally. The lower infectivity of HIV-2, compared to HIV-1, implies that fewer of those exposed to HIV-2 will be infected per exposure. Due to its relatively poor capacity for transmission, HIV-2 is largely confined to West Africa. [21]
Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is the virus that was originally discovered (and initially referred to also as LAV or HTLV-III). It is more virulent, more infective, [99] and is the cause of the majority of HIV infections globally. The lower infectivity of HIV-2 as compared with HIV-1 implies that fewer people ...
This is a timeline of HIV/AIDS, including but not limited to cases before 1980. Pre-1980s See also: Timeline of early HIV/AIDS cases Researchers estimate that some time in the early 20th century, a form of Simian immunodeficiency virus found in chimpanzees (SIVcpz) first entered humans in Central Africa and began circulating in Léopoldville (modern-day Kinshasa) by the 1920s. This gave rise ...
HIV-2 has been found to be less pathogenic than HIV-1. [36] The mechanism of HIV-2 is not clearly defined, nor the difference from HIV-1, however the transmission rate is much lower in HIV-2 than HIV-1. Both viruses can lead to AIDS in infected individuals and both can mutate to develop drug resistance. [34]
In 2008, the sample was tested by researchers, identifying partial HIV viral sequences. [8] The specimen, named DRC60 contained a strain of HIV-1 around 88% similar to LEO70, but was found to be most closely related to HIV-1 (M) subgroup A isolates. These two specimens are significant not only because they are the oldest known specimens of HIV ...
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