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Schamberg's disease is a skin disorder that causes a discoloration of the lower extremities. [4] It usually occurs in the lower extremities and rarely elsewhere. [4] This condition is caused by leaky blood vessels near the surface of the skin. [7] The cause of the leaky capillaries is usually not known. [7]
The management of lipodermatosclerosis may include treating venous insufficiency with leg elevation and elastic compression stockings. [9] In some difficult cases, the condition may be improved with the additional use of the fibrinolytic agent, stanozol. Fibrinolytic agents use an enzymatic action to help dissolve blood clots.
Individuals with Felty's syndrome may also experience fever, weight loss, and/or fatigue. In some cases, affected individuals may have discoloration (abnormal brown pigmentation) of the skin, particularly of the leg, sores (ulcers) on the lower leg, and/or an abnormally large liver (hepatomegaly).
What it looks like: Flea bites appear most often on the feet, ankles, and lower legs, per Cleveland Clinic. After a flea bites you, a small, discolored bump forms and a discolored ring or halo may ...
Typical purpura on lower leg More severe case of HSP on child's foot, leg, and arm. Purpura, arthritis, and abdominal pain are known as the "classic triad" of Henoch–Schönlein purpura. [5] Purpura occur in all cases, joint pains and arthritis in 80%, and abdominal pain in 62%.
It is blue in color as its melanocytes are very deep in the skin. Characteristic pigmented melanocytes between bundles of collagen. H&E stain. Spitz nevus: A distinct variant of intradermal nevus, usually in a child. They are raised and reddish (non-pigmented). Characteristic vertically arranged nests of cells ("hanging bananas"). H&E stain.
Women, people with another autoimmune condition (like type 1 diabetes), and people between the ages of 30 to 60 are all at a greater risk of developing Graves’ disease, per Mayo Clinic.
Lymphedema can occur in both the upper and lower extremities, and in some cases, the head and neck. Assessment of the extremities first begins with a visual inspection; color, presence of hair, visible veins, size and any sores or ulcerations are noted. Lack of hair may indicate an arterial circulation problem. [34]