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Dexamethasone is a fluorinated glucocorticoid medication [10] used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease (COPD), croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), [11] and along with antibiotics in tuberculosis. [10]
Most esters of these corticosteroids are not included in this list; for esters, see here instead. The most common structural modifications in synthetic corticosteroids include 1(2)- dehydrogenation , 6α-, 9α-, 16α-, and 16β- substitution (with a halogen or methyl group ), 16α,17α- acetonidation , and 17α- and 21- esterification .
Dexamethasone acts as an anti-inflammatory corticosteroid. [1] In 2022, it was the 286th most commonly prescribed medication in the United States, with more than 500,000 prescriptions. [ 3 ] [ 4 ]
Tacrolimus (trade names Prograf, Astagraf XL, Envarsus XR) is a product of the bacterium Streptomyces tsukubensis. It is a macrolide lactone and acts by inhibiting calcineurin. The drug is used primarily in liver and kidney transplantations, although in some clinics it is used in heart, lung, and heart/lung transplantations.
Trade names: Levodexa: Routes of ... ATC code: S01CA01 ; Legal status; Legal status: CA: ℞-only [1] [2] Dexamethasone ... is a fixed-dose combination medication ...
Dexamethasone isonicotinate is an anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, locally, and parenterally. [ 1 ] [ 2 ] [ additional citation(s) needed ] It may cause salt and water retention .
Bortezomib/dexamethasone is a combination drug against multiple myeloma. [1] When bortezomib is used by the trade name Velcade, the combination is called Vel/Dex (or Vel-Dex or Veldex). Bortezomib is a proteasome inhibitor and dexamethasone is a corticosteroid.
Tobramycin/dexamethasone, sold under the brand name Tobradex, is a fixed-dose combination medication in the form of eye drops and eye ointment, marketed by Alcon. [1] [2] [3] The active ingredients are tobramycin (an antibiotic) and dexamethasone (a corticosteroid). [2] It is prescribed for the treatment of pink eye in combination with ...