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  2. Clinodactyly - Wikipedia

    en.wikipedia.org/wiki/Clinodactyly

    Clinodactyly is an autosomal dominant trait that has variable expressiveness and incomplete penetrance. [citation needed]Clinodactyly can be passed through inheritance and presents as either an isolated anomaly or a component manifestation of a genetic syndrome. [2]

  3. Arachnodactyly - Wikipedia

    en.wikipedia.org/wiki/Arachnodactyly

    Causes Mutations in the fibrillin-2 gene, in chromosome 5q23, or the fibrillin-1 gene, at chromosome 15q21.1 Arachnodactyly (" spider fingers ") is a medical condition that is characterized by fingers and toes that are abnormally long and slender, in comparison to the palm of the hand and arch of the foot.

  4. Nail clubbing - Wikipedia

    en.wikipedia.org/wiki/Nail_clubbing

    Nail clubbing, also known as digital clubbing or clubbing, is a deformity of the finger or toe nails associated with a number of diseases, anomalies and defects, some congenital, mostly of the heart and lungs. [2] [3] When it occurs together with joint effusions, joint pains, and abnormal skin and bone growth it is known as hypertrophic ...

  5. Harlequin-type ichthyosis - Wikipedia

    en.wikipedia.org/wiki/Harlequin-type_ichthyosis

    Harlequin-type ichthyosis is caused by mutations in the ABCA12 gene. [4] This gene codes for a protein necessary for transporting lipids out of cells in the outermost layer of skin. [4] The disorder is autosomal recessive and inherited from parents who are carriers. [4] Diagnosis is often based on appearance at birth and confirmed by genetic ...

  6. Genodermatosis - Wikipedia

    en.wikipedia.org/wiki/Genodermatosis

    Genodermatosis is a hereditary skin disease with three inherited modes including single gene inheritance, multiple gene inheritance and chromosome inheritance. [1] There are many different types of genodermatosis; the prevalence of genodermatosis ranges from 1 per 6000 people to 1 per 500,000 people. [2]

  7. Rare disorder can turn fingers and toes white or blue when it ...

    www.aol.com/lifestyle/rare-disorder-turn-fingers...

    Primary Raynaud’s — also called Raynaud’s disease — happens on its own and patients first notice the distinctive color changes in their teens or 20s. This is the type Smith was diagnosed ...

  8. Rubinstein–Taybi syndrome - Wikipedia

    en.wikipedia.org/wiki/Rubinstein–Taybi_syndrome

    Facial features (A), left hand and feet showing broad thumb and big toes (B, C) and X-ray of both hands showing short broad thumbs (D). (Limb Malformations & Skeletal Dysplasia) Rubinstein–Taybi syndrome presents itself from birth, and is usually hallmarked by delayed physical and cognitive growth. [citation needed]

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