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Hepatic artery embolization, also known as trans-arterial embolization (TAE), is one of the several therapeutic methods to treat primary liver tumors or metastases to the liver. The embolization therapy can reduce the size of the tumor, and decrease the tumor's impact such its hormone production, effectively decreasing symptoms.
A liver metastasis is a malignant tumor in the liver that has spread from another organ that is affected by cancer. The liver is a common site for metastatic disease because of its rich, dual blood supply (the liver receives blood via the hepatic artery and portal vein).
Hepatic arterial infusion (HAI) is a medical procedure that delivers chemotherapy directly to the liver.The procedure, mostly used in combination with systemic chemotherapy, plays a role in the treatment of liver metastases in patients with colorectal cancer (CRC). [1]
Patients with hepatic metastatic disease from neuroendocrine tumors, gastrointestinal stromal tumors and other sarcomas, ocular melanoma, and some "hypervascular" metastases (such as those from breast cancer or renal cell cancer) may also be candidates for bland embolization, assuming the liver is the only site of disease, or when the procedure ...
Candidates for radioembolization include patients with: Unresectable liver cancer of primary or secondary origin, such as hepatocellular carcinoma [4] and liver-metastases from a different origin (e.g. colorectal cancer, [5] breast cancer, [6] neuroendocrine cancer, [7] cholangiocarcinoma [8] or soft tissue sarcomas [9])
This pre-treatment causes the tumors to shrink, resulting in a larger proportion of liver tissue that is functional, with broader margins. [citation needed] Preoperative evaluation involves imaging of the liver and its metastases, for example with ultrasound, computed tomography or magnetic resonance imaging.
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