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Some well-known rickettsial diseases include: Rickettsialpox - caused by Rickettsia akari, this disease is transmitted by mite bites and is generally milder than other rickettsial infections. Rocky Mountain spotted fever - caused by Rickettsia rickettsii, this disease is transmitted by tick bites and is prevalent in the Americas.
The disease is caused by Rickettsia rickettsii, a type of bacterium that is primarily spread to humans by American dog ticks, Rocky Mountain wood ticks, and brown dog ticks. [4] Rarely the disease is spread by blood transfusions. [4] Diagnosis in the early stages is difficult. [5]
Rickettsia is a genus of nonmotile, gram-negative, nonspore-forming, highly pleomorphic bacteria that may occur in the forms of cocci (0.1 μm in diameter), bacilli (1–4 μm long), or threads (up to about 10 μm long).
Rickettsia conorii is a Gram-negative, obligate intracellular bacterium of the genus Rickettsia that causes human disease called boutonneuse fever, Mediterranean spotted fever, Israeli tick typhus, Astrakhan spotted fever, Kenya tick typhus, Indian tick typhus, or other names that designate the locality of occurrence while having distinct clinical features.
However, scrub typhus is still considered a rickettsiosis, even though the causative organism has been reclassified from Rickettsia tsutsugamushi to Orientia tsutsugamushi. [citation needed] Examples of rickettsioses include typhus, both endemic and epidemic, Rocky Mountain spotted fever, and Rickettsialpox.
Rickettsialpox is a mite-borne infectious illness caused by bacteria of the genus Rickettsia (Rickettsia akari). [1] Physician Robert Huebner and self-trained entomologist Charles Pomerantz played major roles in identifying the cause of the disease after an outbreak in 1946 in a New York City apartment complex, documented in "The Alerting of Mr. Pomerantz," an article by medical writer Berton ...
It is suggested that the Sca2 gene, which is an actin-polymerizing determinant, is a distinguishing factor for the Rickettsia family, as R. rickettsii mutants with a Sca2 transposon the bacteria can avoid autophagic processes by host phagocytic cells. This leads to an increase in disease manifestation for the host.
Spotted fever rickettsiosis, also known as spotted fever group rickettsia (SFGR), is a group of infections that include Rocky Mountain spotted fever, Rickettsia parkeri rickettsiosis, Pacific Coast tick fever, and rickettsialpox. [2] The group of infections was created in 2010 as they are difficult to tell apart. [2]