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Scutellaria galericulata, the common skullcap, marsh skullcap [5] or hooded skullcap, is a hardy perennial herb native to northern areas of the Northern Hemisphere, including Europe, Asia, and almost all of Canada. It is a member of the mint family.
[5] [6] Most of the flowers do not appear at the top of the main stem but are produced along the length of side branches that grow from the leaf axils. Other skullcaps (Scutellaria) species include common skullcap (S. galericulata), western skullcap (S. canescens), and southern skullcap (S. cordifolia).
[3] [4] [5] In mice, baicalin produces anxiolytic effects without sedative or myorelaxant effects. [6] [7] It is thought that baicalin, along with other flavonoids, may underlie the anxiolytic effects of S. baicalensis and S. lateriflora. [8] [9] Baicalin is a known prolyl endopeptidase inhibitor. [10] It induces apoptosis in pancreatic cancer ...
Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation, or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life threatening or lethal." [3]
Scutellaria is a genus of flowering plants in the mint family, Lamiaceae.They are known commonly as skullcaps. [2] The generic name is derived from the Latin scutella, meaning "a small dish, tray or platter", [3] or "little dish", [4] referring to the shape of the calyx. [4]
The compound is found only in trace amounts in the "Chinese skullcap" Scutellaria baicalensis, another plant used in traditional Chinese medicine. The determination of the structure of scutellarin took Guido Goldschmiedt many years: after the first publication on that topic in 1901, only in 1910 he managed to obtain enough starting material for ...