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Fractionation makes it possible to isolate more than two components in a mixture in a single run. This property sets it apart from other separation techniques. Fractionation is widely employed in many branches of science and technology. Mixtures of liquids and gasses are separated by fractional distillation by difference in boiling point.
In chemistry, fractional crystallization is a stage-wise separation technique that relies on the liquid–solid phase change. This technique fractionates via differences in crystallization temperature and enables the purification of multi-component mixtures, as long as none of the constituents can act as solvents to the others.
Fractionation refers to a purification strategy in which some relatively inefficient purification method is repeatedly applied to isolate the desired substance in progressively greater purity. Electrolysis refers to the breakdown of substances using an electric current. This removes impurities in a substance that an electric current is run through
Design and operation of a distillation column depends on the feed and desired products. Given a simple, binary component feed, analytical methods such as the McCabe–Thiele method [4] [6] [7] or the Fenske equation [4] can be used. For a multi-component feed, simulation models are used both for design and operation.
Field-flow fractionation, abbreviated FFF, [1] is a separation technique invented by J. Calvin Giddings. The technique is based on separation of colloidal or high molecular weight substances in liquid solutions, flowing through the separation platform, which does not have a stationary phase .
In most cases the fractionation of polymers on a preparative scale is based on chromatographic methods (e.g. preparative SEC or Baker-Williams fractionation).Therefore, the production is normally limited to few grams only.
A fraction in chemistry is a quantity collected from a batch of a substance in a fractionating separation process. In such a process, a mixture is separated into fractions, which have compositions that vary according to a gradient. A fraction can be defined as a group of chemicals that have similar boiling points.
Salting out (also known as salt-induced precipitation, salt fractionation, anti-solvent crystallization, precipitation crystallization, or drowning out) [1] is a purification technique that utilizes the reduced solubility of certain molecules in a solution of very high ionic strength.