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Pyrogen may refer to: Pyrogen (fever), a fever inducing substance. Pyrogen (pyrotechnics), a pyrotechnic composition producing flame when heated by e.g. a bridgewire
Depyrogenation refers to the removal of pyrogens from solutions, most commonly from injectable pharmaceuticals.. A pyrogen is defined as any substance that can cause a fever. . Bacterial pyrogens include endotoxins and exotoxins, although many pyrogens are endogenous to the ho
Electric matches consist of two parts, a bridgewire and a pyrogen. The bridgewire is a heating element, typically in the form of a loop or coil of thin wire, which is encased in the pyrogen, which is a quantity of readily ignited pyrotechnic initiator composition. If the pyrogen is sufficiently conductive, it can act as the bridgewire as well.
The energetic material used, often called pyrogen, is usually a pyrotechnic composition made of a fuel and oxidizer, where the fuel produces a significant amount of hot particles that cause/promote the ignition of the desired material.
But pyrogens include non-endotoxic substances (derived from microorganisms other than gram-negative-bacteria or from chemical substances) as well. [90] The types of pyrogens include internal (endogenous) and external (exogenous) to the body.
Streptococcus pyogenes is a species of Gram-positive, aerotolerant bacteria in the genus Streptococcus.These bacteria are extracellular, and made up of non-motile and non-sporing cocci (round cells) that tend to link in chains.
Lipopolysaccharides can have substantial impacts on human health, primarily through interactions with the immune system. LPS is a potent activator of the immune system and is a pyrogen (agent that causes fever). [4] In severe cases, LPS can trigger a brisk host response and multiple types of acute organ failure [5] which can lead to septic ...
The fever-producing property of human leukocytic pyrogen (interleukin 1) was purified by Dinarello in 1977 with a specific activity of 10–20 nanograms/kg. [9] In 1979, Dinarello reported that purified human leukocytic pyrogen was the same molecule that was described by Igal Gery in 1972.