Ads
related to: does magnesium interfere with doxycycline interaction with one
Search results
Results From The WOW.Com Content Network
Many drug interactions are due to alterations in drug metabolism. [12] Further, human drug-metabolizing enzymes are typically activated through the engagement of nuclear receptors. [12] One notable system involved in metabolic drug interactions is the enzyme system comprising the cytochrome P450 oxidases.
A classic example of this effect is the interaction between β-lactams, which damage the bacteria cell membrane, and aminoglycosides, which inhibit protein synthesis. [1] The damage dealt to the cell wall by β-lactams allows more aminoglycoside molecules to be taken up into the cell than would otherwise be possible, enhancing cell damage. [ 1 ]
Excessive magnesium intake from dietary supplements or medications can cause magnesium toxicity. [1] Magnesium can also interact negatively with several medication types, such as antibiotics and diuretics, so people taking medications regularly should consult with a healthcare provider before starting a magnesium supplement. [1]
Magnesium for constipation is a doctor-approved treatment. Experts recommend magnesium citrate or magnesium oxide, and say the oral route is most effective. ... Magnesium may interact with some ...
Partial exceptions to these rules occur for doxycycline and minocycline, which may be taken with food (though not iron, antacids, or calcium supplements). Minocycline can be taken with dairy products because it does not chelate calcium as readily, although dairy products do decrease absorption of minocycline slightly. [39]
Doxycycline absorption is also inhibited by divalent and trivalent cations, such as iron, bismuth, aluminum, calcium and magnesium. [15] Doxycycline forms unstable complexes with metal ions in the acidic gastric environment, which dissociate in the small intestine, allowing the drug to be absorbed.
Magnesium is absorbed orally at about 30% bioavailability from any water soluble salt, such as magnesium chloride or magnesium citrate. The citrate is the least expensive soluble (high bioavailability) oral magnesium salt available in supplements, with 100 mg and 200 mg magnesium typically contained per capsule, tablet or 50 mg/mL in solution. [26]
Main page; Contents; Current events; Random article; About Wikipedia; Contact us