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Chloramphenicol may cause bone marrow suppression during treatment; this is a direct toxic effect of the drug on human mitochondria. [23] This effect manifests first as a fall in hemoglobin levels, which occurs quite predictably once a cumulative dose of 20 g has been given. The anaemia is fully reversible once the drug is stopped and does not ...
Since the syndrome is due to the accumulation of chloramphenicol, the signs and symptoms are dose related. [10] According to Kasten's review published in the Mayo Clinic Proceedings, a serum concentration of more than 50 μg/mL is a warning sign, [10] while Hammett-Stabler and John states that the common therapeutics peak level is 10-20 μg/mL and is expected to achieve after 0.5-1.5 hours of ...
Thiamphenicol is also widely used in Brazil, particularly for the treatment of sexually transmitted infections such as pelvic inflammatory disease. [3] Unlike chloramphenicol, thiamphenicol is not readily metabolized in cattle, poultry, sheep, or humans, but is predominantly excreted unchanged.
Chloramphenicol — formerly first-line therapy for Rocky Mountain spotted fever (until doxycycline became available). [4] Also first-line therapy (used topically) for bacterial conjunctivitis , and systemically for meningitis when allergies to penicillin or cephalosporin exist.
Exceptionally, an agent may be classified in this group solely on the basis of limited evidence of carcinogenicity in humans. This list is focusing on the hazard linked to the agents. This means that the carcinogenic agents are capable of causing cancer, but this does not take their risk into account, which is the probability of causing a ...
The agents said they found about 40 human skulls, spinal cords, femurs and hip bones in Nott’s apartment, along with a Harvard Medical School bag.
A substance intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease. A substance recognized by an official pharmacopeia or formulary . Biological products are included within this definition and are generally covered by the same laws and regulations, but differences exist regarding their manufacturing processes ...
Is Chloramphenicol used in the treatment of animals? —The preceding unsigned comment was added by Frederickwolf (talk • contribs) 19:07, 15 December 2006 (UTC). Chloramphenicol is widely used in aquarium. Chloramphenicol is effective in GI problems of fish in most cases as a medicinary bath. The dose should be 250mg/25L of water.